Beitragstitel | Posttherapeutic detection of local recurrence or persistence in head and neck cancer: A comparison of endoscopic control with biopsy versus CT-scan imaging |
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Beitragscode | P32 |
Autor:innen | |
Präsentationsform | Poster |
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Abstract-Text |
Objectives: The aim of the study is to evaluate the timing and and best diagnostic method of detecting local recurrence or persistence of head & neck cancer after treatment. CT-scan imaging was compared to endoscopic control with biopsy. Material and Methods: Between 2011-2017, 98 endoscopic controls had been performed generally 3 months after treatment in the Departement of Otorhinolaryngology, Head & Neck Surgery of the Kantonsspital Aarau. In this retrospective investigation 49 cases were selected that had control imaging taken and a biopsy with histologic examination was performed additionally. The sensitivity and specificity of these diagnostic methods was assessed and compared. Results: Imaging studies demonstrated a moderate sensitivity of 62,5 %, however specificity (36,59 %) was low. Among 16 cases, where malignancy was excluded by imaging, 15 were also histologically negative (12,5 % false negative). However 14 highly suspicious imaging studies showed histological signs for malignancy in only 5 cases (63,4 % false positive). If endoscopic biopsy was only performed in patients with highly suspicious (n=14) or unclear imaging studies (n=19), one patient with histologically verified carcinoma would have been missed. Conclusion: Detecting local recurrence or persistence in head & neck cancer is crucial. CT-scan imaging alone serves as a moderate diagnostic tool. Therefore we highly recommend additional endoscopic control with biopsy about three months after completion of treatment. |